We, without the new power-up of Granola, have already seen the new Dragon Ball Super manga villains main ability. The ability that I am talking about is Granola being a natural sharp-shooter. If Granola was to engage in this battle systematically, he won’t risk charging head-on and instead, take one out before the fighting even begins.
This way, it increases the chances of victory and reduced the chances of injury, with injuries possibly further delaying his future battle against Frieza. Now, if Granola was to use this sniping ability against Vegeta, he will likely fail in his attempt to take out the Saiyan but against Goku, Granola will likely be victorious.
Remember, if Goku isn’t in his Ultra Instinct form, he becomes quite venerable to sneak attacks. This is a weakness of his, which has been pointed out continuously in Dragon Ball Super. If Granola was to attempt to take out Goku in this fashion and he was not in an Ultra Instinct state, it’s possible for Granola to win. Then, Granola can take on Vegeta in a one-on-one battle but it’s unknown what that result will be, as we are yet to see the full power of Granola. However, there is no way Vegeta would fall for a trick like sniping, which causes Granola’s only known ability to be rendered useless.