Finally, the highly anticipated Boruto manga chapter 48 was released and we watched a number of things unfold. First of all and most importantly, we discovered that Jigen only has three days remaining to live and of course, he isn’t going to sit around and wait for death.
In fact, he is heading to where Kawaki is being held in order to implant another Karma seal and be reborn once again. This is his only chance at life as no other vessel will be efficient and put him in the same position as now.
This has resulted in Jigen appearing at the gates of Konoha, a very nostalgic scene, which you might remember from back in Naruto Shippuden when Pain destroyed Konoha. There is nothing going to stop Jigen from taking Kawaki and we know from the glimpses in the future at the start of Boruto, Kawaki will get his seal again, which means that Jigen will likely be successful now.
Both Naruto and Sasuke will attempt to stop him but Jigen is stronger now than what he was before and before, Naruto and Sasuke were not enough to defeat him. However, we do know that Kashin Koji escaped and will likely make his way to Konoha to help both Sasuke and Naruto. Although, Koji is badly injured so, I doubt he will do much.
Therefore, it’s more likely that Jigen will win and that could mean the destruction of Konoha is basically confirmed in Boruto Naruto Next Generations manga chapter 49. Jigen will not stop until he finds Kawaki and Konoha will try to stop him. This may lead to many casualties and I doubt Jigen will be bringing anyone back from the dead like Nagato did.
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